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KMID : 0367419760170060039
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Journal of Korean Pediatric Society
1976 Volume.17 No. 6 p.39 ~ p.44
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Systemic Cryptococcosis
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김석곤/Kim, S.K.
남기종/신성희/김기준/정동규/Nam, K.J./Shin, S.H./Kim, K.J./Chung, D.K.
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Abstract
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Cryptococcal infection is now not so rare a disease in Far East Asia. The authors present two cascs of systemic cryptococcosis experienced in our pediatric- department. Casel had involvement of the liver, spleen, kidney, lymph rocks, adrenal glands and brain, and case 11 C.N.S. and liver. Numerous cryptococcus -neoformar_swere found in the affected organs and tissues.
The authors discuss incidence, diagnostic problems and drugs. Routine India ink preperation and repeat of spinal fluid examinaton were emphasized in the case sof meningitis. In ambiguous cases, urine, sputum, blcod, bone marrow and stool examination can help identify a fungus infection.
Amphotericin-B is the most effective drug to combat fungal infection up to present. 5-fluorocytocine is a new drug, but more evaluation is required because of little experience with it.
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KEYWORD
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